Response of bispectral index to neuromuscular block in awake volunteers

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The bispectral index declines during neuromuscular block in fully awake persons.

UNLABELLED Bispectral index (BIS) is an electroencephalographic variable promoted for measuring depth of anesthesia. Electromyographic activity influences surface electroencephalography and the calculation of BIS. In this study, we sought to determine the effect of spontaneous electromyographic activity on BIS. BIS was monitored in three volunteers by using an Aspect A-1000 monitor. The experim...

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Low bispectral index values in awake volunteers receiving a combination of propofol and midazolam.

THE Bispectral Index (BIS) is increasingly used to monitor the level of (un)consciousness during surgical anesthesia and conscious sedation. Generally, an intraoperative BIS of 40–60 is considered sufficient to maintain adequate hypnosis for surgery. Recently, a new version of the BIS monitor has been introduced: the BIS-XP (Aspect Medical Systems, Newton, MA). The BIS-XP is said to exhibit imp...

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Normal bispectral index values in healthy volunteers.

To the Editor:—We read with great scientific interest the study of Vuyk et al. reporting three cases in which volunteers receiving combinations of propofol and midazolam remained responsive to verbal command although the Bispectral Index (BIS) values were at, or just above, 40, the area considered to be associated with adequate hypnosis for surgery (BIS, 40–60). Vuyk et al. note that the electr...

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Effects of stellate ganglion block on sedation as assessed by bispectral index in normal healthy volunteers.

BACKGROUND The sympathetic nervous system plays an important role in the arousal response. Recently, the stellate ganglion block (SGB) was found to effectively treat anxiety and night awakening in humans and decrease electroencephalogram (EEG) indices of arousal responses in rat. But, the role of the sympathetic block in human arousal responses has not yet been studied. OBJECTIVE We performed...

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Effect of sugammadex or neostigmine neuromuscular block reversal on bispectral index monitoring of propofol/remifentanil anaesthesia.

BACKGROUND Sugammadex is a modified γ-cyclodextrin with a novel mechanism of action for reversing the steroidal neuromuscular blocking agent rocuronium. Bispectral index (BIS) is an EEG-derived measure which can be sensitive to frontal electromyographic (EMG) artifacts. We compared BIS values before and after sugammadex or neostigmine neuromuscular block (NMB) reversal in patients with or witho...

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ژورنال

عنوان ژورنال: British Journal of Anaesthesia

سال: 2015

ISSN: 0007-0912

DOI: 10.1093/bja/aev072